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Table 2 Results of three meta-analyses of preoperative RT versus surgery alone in resectable rectal cancer.

From: The use of preoperative radiotherapy in the management of patients with clinically resectable rectal cancer: a practice guideline

Outcome

Pooled Results Odds Ratio, 95% Confidence Interval and p value

 

Camma et al [35]

CRCCG [36]*

Present Review

Overall Mortality

0.84 (0.72, 0.98)

p = 0.03

0.95 (0.86, 1.06)

p = 0.34

0.85 (0.74, 0.97)

p = 0.019

Local Failure

0.49 (0.38, 0.62)

p < 0.001

0.58 (0.42, 0.80)

p = 0.00008

0.62 (0.45, 0.85)

p = 0.0029

30-day Postoperative Mortality

1.38 (0.86, 2.32)

p = 0.22

-

-

1.42 (0.90, 2.23)

p = 0.13

  1. * ORs calculated from data shown in Figure 1[35].