Figure 4From: Perinatal nicotine exposure induces asthma in second generation offspring Effect of perinatal nicotine exposure on acetylcholine tracheal constriction response in F1 and F2 offspring. Compared to the control group, with nicotine administration there was a significant increase in tracheal constriction in response to acetylcholine only in the males of both the F1 and F2 generations. Values are means ± SE; * P < 0.05, ** P < 0.01, versus control group; n = 5 to 6.Back to article page