Author (year) | Population representativeness | Adequacy of sequence generation | Masking/selection bias | Intention to treat | Incomplete outcome data | Loss to follow up | Sample size | Grade of quality |
---|---|---|---|---|---|---|---|---|
Polley et al. 2002 [32] | Yes | Yes: | No | Not reported | No | Yes | 120 | Low |
Hui et al. (2006) [33] | Yes: from clinic | Exact method not described | No | Not reported | No | Yes | 52 | Low |
Wolff et al., 2008 [30] | Yes | Yes: computer generated | No | Not reported | Yes | Yes | 50 | Low |
Jeffries et al., 2009 [28] | Yes | Yes: Opaque envelope | Yes | Not reported | Yes | Yes | 286 | Low |
Ong et al., 2009 [42] | Yes | Exact method not described | No | Not reported | No | No | 12 | Low |
Barakat et al., 2011 [41] | Yes | Yes | Yes | Yes | Yes | Yes | 160 | Medium |
Asbee et al. 2009 [27] | Yes | Yes | No | Not reported | Yes | No | 100 | Low |
Thornton et al., 2009 [29] | Yes | Yes | Yes | Not reported | Yes | Yes | 257 | Medium |
Guelinckx et al., 2010 [26] | Not reported | Randomised but not reported how | Not reported | Not reported | Yes | Not reported | 99 | Low |
Phelan et al., 2011 [34] | Yes | Yes: Opaque envelope | Yes | Yes | Yes | Yes | 401 | Medium, |
Quinlivan et al., 2011 [59] | Yes | Yes: Opaque envelope | Yes | Yes | Yes | Yes | 124 | Medium |
Luoto et al., 2011 [43] | Yes | Yes | Yes | Yes | Yes | Yes | 399 | Medium |
Nascimento et al., 2011 [44] | Yes | Yes: Opaque envelope | Yes | Yes | Yes | Yes | 82 | Low |