Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration

Table 6 Relation between marker (E-Cadherin) and patient characteristics [182].

	E-Cadherin staining index^a
	Low		High
Variable	Number of patients	%	Number of patients	%
Histologic type
Endometrioid^b	135	53	120	47
Clear-cell or serous papillary	24	83	5	17
FIGO grade
1	25	49	26	51
2	63	51	61	49
3	71	65	38	35
Vascular invasion
0 or 1 vessel	94	52	88	48
≥2 vessels	65	64	37	36
Myometrial infiltration^c, %
<50	77	51	74	49
≥50	67	66	35	34
FIGO stage^d
I or II	120	53	108	47
III or IV	39	71	16	29

^aResults available in 284 patients; ^bAdenosquamous and adenoacanthoma are included; ^cInformation available in 253 patients (E-cadherin) and 255 patients (beta-catenin); ^dData missing in one patient.

ISSN: 1741-7015