| FeSO4 | Placebo | Treatment effecta | ||
---|---|---|---|---|---|
 | n = 74 mean (SD) | n = 71 mean (SD) | Crude ITT group difference Δ (95%CI) | Significance level LR test | Adjusted effectb Δ (CI95%) |
Visual analogue scale fatigue | 3.4 (2.4) | 3.5 (2.5) | -0.15 (-0.9 to 0.6) | P = 0.697 | -0.18 (-0.9 to 0.6) |
Fatigue severity scalec | 2.5 (1.3) | 2.6 (1.5) | -0.06 (-0.4 to 0.3) | P = 0.760 | -0.05 (-0.4 to 0.3) |
Vitality item (SF-12V2)d | 53.6 (12.7) | 55.3 (12.3) | -0.24 (-3.9 to 3.4) | P = 0.897 | -0.13 (-3.8 to 3.6) |
Chester step test, mLO2/kg/minc | 40.5 (14.5) | 40.1 (17.0) | 0.28 (-4.5 to 5.1) | P = 0.907 | 0.02 (-4.8 to 4.8) |
Hemoglobin, g/L | 135 (6.7) | 130 (5.3) | 5.2 (3.5 to 6.9) | P < 0.001 | 5.3 (3.7 to 7.0) |
Ferritin, ng/mL | 28.0 (9.8) | 12.9 (8.3) | 14.8 (12.2 to 17.4) | P < 0.001 | 15.1 (12.6 to 17.6) |
Quality of life (SF-12NL)e | Â | Â | Â | Â | Â |
   Physical condition | 54.8 (3.3) | 52.4 (5.2) | 2.4 (1.1 to 3.7) | P < 0.001 | 2.4 (1.1 to 3.7) |
   Mental health | 40.1 (4.8) | 40.7 (4.8) | -0.4 (-2.0 to 1.2) | P = 0.590 | -0.5 (-2.0 to 1.1) |