Table 3 Characteristics of hospitalized adults who tested positive (cases) and negative (controls) for Clostridium difficile
From: Depression, antidepressant medications, and risk of Clostridium difficileinfection
Characteristics | Cases, n = 468 | Controls, n = 3579 | Pvalue |
|---|---|---|---|
Age, mean ± SDa | 57.6 ± 17.5 | 58.8 ± 16.5 | 0.158 |
Female, n (%) | 223 (47.6) | 1723 (48.1) | 0.841 |
Caucasian, n (%) | 387 (82.7) | 2927 (81.8) | |
African-American, n (%) | 51 (10.9) | 386 (10.8) | |
Other race/unknown, n (%) | 30 (6.4) | 266 (7.4) | 0.727 |
Elective admission, n (%) | 138 (29.5) | 930 (26.0) | |
Urgent admission, n (%) | 104 (22.2) | 846 (23.6) | |
Emergent admission, n (%) | 226 (48.3) | 1803 (50.4) | 0.268 |
Days until stool collection, median (IQR)b | 6 (4 to 10) | 6 (4 to 10) | 0.273 |
Antibiotics, n (%) | 392 (83.8) | 2956 (82.6) | 0.530 |
Immunosuppressants, n (%) | 71 (36.4) | 554 (35.0) | 0.692 |
Proton-pump inhibitors, n (%) | 268 (57.3) | 2040 (57.0) | 0.913 |
Histamine-2 receptor antagonists, n (%) | 138 (29.5) | 1061 (29.6) | 0.944 |
Statins, n (%) | 130 (27.8) | 927 (25.9) | 0.385 |
Anxiolytics, n (%) | 67 (34.4) | 499 (31.5) | 0.419 |
Antipsychotics, n (%) | 24 (12.3) | 202 (12.7) | 0.860 |