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Table 2 Advantages and disadvantages of invasive diagnostic methods for diagnosis of chronic cerebrospinal venous insufficiency

From: The role of noninvasive and invasive diagnostic imaging techniques for detection of extra-cranial venous system anomalies and developmental variants

Invasive diagnostic methods

Advantages

Disadvantages

Catheter venography[28, 34, 42, 43, 4551]

- considered gold standard

- invasive method

- real time information can be obtained by using contrast

- ionizing radiation

- ability to measure pressure

- cannot be performed without contrast (allergy, toxicity)

- provide “road map” for planning endovascular procedures

- operator dependent

- can be complemented by use of more sophisticated criteria (time to empty contrast from vein or wasting of the balloon)

- time consuming (>45 minutes)

 

- cannot detect intra-luminal abnormalities

- no global view of veins and collaterals

- no standardized definition of significant vein stenoses

Intravascular ultrasound[47, 107, 108]

- offers a 360° view of the vessel’s wall from the inside

- invasive method

- can detect intra-luminal abnormalities

- lack of experience - no standardized protocols

- easily accesses all parts of IJVs in comparison with DS

- ring down artifacts

- provides more accurate assessment of vein stenosis and wall thickness than CV and DS

- geometric distortion - from imaging in an oblique plane

  

- size of IVUS probe - limitation in the imaging of severe stenosis

  1. Legend: CV, catheter venography; DS, Doppler Sonography; IVUS, intravascular ultrasound.