Table 5 Rate ratios for immune-mediated diseases following admission for vitamin D deficiency (coded as such)
Autoimmune condition | O | E | RR (95% CI) | P-value |
|---|---|---|---|---|
Addison’s disease | 12 | 1.7 | 7.0 (3.6 to 12.3) | <0.001 |
Ankylosing spondylitis | 10 | 5.3 | 1.9 (0.9 to 3.5) | 0.06 |
Asthma (aged 5 to 54) | 83 | 278.9 | 0.3 (0.2 to 0.4) | <0.001 |
Celiac disease | 38 | 8.6 | 4.4 (3.1 to 6.1) | <0.001 |
Crohn’s disease | 33 | 10 | 3.3 (2.3 to 4.6) | <0.001 |
Diabetes mellitus (aged 0 to 29) | 20 | 6.2 | 3.2 (2.0 to 5.0) | <0.001 |
Idiopathic thrombocyt. purpura | 5 | 5 | 1.0 (0.3 to 2.3) | 0.83 |
Multiple sclerosis | 12 | 8.2 | 1.5 (0.8 to 2.6) | 0.25 |
Myxoedema | 177 | 328.2 | 0.5 (0.5 to 0.6) | <0.001 |
Pemphigoid | 10 | 2.7 | 3.7 (1.8 to 6.8) | <0.001 |
Pernicious anemia | 34 | 19.6 | 1.7 (1.2 to 2.4) | 0.002 |
Primary biliary cirrhosis | 7 | 2.4 | 2.9 (1.2 to 6.0) | 0.008 |
Psoriasis | 18 | 28.9 | 0.6 (0.4 to 1.0) | 0.05 |
Rheumatoid arthritis | 101 | 74.5 | 1.4 (1.1 to 1.7) | 0.003 |
Sjogren’s syndrome | 12 | 5.7 | 2.1 (1.1 to 3.7) | 0.01 |
Systemic lupus erythematosus | 28 | 5.3 | 5.3 (3.5 to 7.7) | <0.001 |
Thyrotoxicosis | 67 | 35.9 | 1.9 (1.5 to 2.4) | <0.001 |
Ulcerative colitis | 21 | 13.6 | 1.5 (0.9 to 2.3) | 0.06 |