Figure 1

Mitochondrial reactive oxygen species generation in patients with inflammatory bowel disease. (A) Intracellular H₂O₂ and mitochondrial peroxynitrate levels in mononuclear cells of patients with IBD before (IBD untr) and after treatment (IBD treat), compared with healthy volunteers (cont). Results are expressed as means ±SE. *P <0.003, **P <0.001. (B) Western blotting analysis of the expression patterns of various mtETC complex subunits from mitochondria isolated from peripheral blood MNC of patients. pat – patient. IBD, inflammatory bowel disease; mtETC, mitochondrial electron transport chain; MNC, mononuclear cells.