Study [reference]: countries | Population | n | Efficacy | Lower bound of 95% CI | Adherencea |
---|---|---|---|---|---|
Partners PrEP [8]: Kenya, Uganda | Heterosexual couples | 4758 | 67% TDF; 75% TDF/FTC | 44% TDF; 55% TDF/FTC | 82% |
TDF2 Study [9]: Botswana | Young men and women | 1219 | 62% TDF/FTC | 21.5% | 80% |
Bangkok TDF [12]: Thailand | IVDU | 2413 | 49% TDF | 9.6% | 67% |
iPrEx [7]: S. America, SA, Thailand, USA | MSM | 2499 | 44% TDF/FTC | 15% | 51% |
FEM-PrEP [10]: Kenya, SA, Tanzania | Young women | 2120 | 6% TDF/FTC | −52% | 37% |
VOICE [11]: South Africa, Uganda, Zimbabwe | Young women | 5029 | −49% TDF; - 4% TDF/FTC | −130% TDF; −50% TDF/FTC | 30% |