Table 2 Commercially available LPAs for TB detection in clinical specimens
Assay | Manufacturer | Method | Material | Sensitivity,% (95% CI) | Specificity,% (95% CI) | References |
|---|---|---|---|---|---|---|
INNO-LiPA Rif.TB | InnoGenetics, Gent, Belgium | PCR amplification/hybridization | DNA from decontaminated smear-positive sputum | 93.0 (92.0 to 94.0) | 83.0 (81.0 to 85.0) | |
INNO-LiPA Rif.TB | InnoGenetics, Gent, Belgium | PCR amplification/hybridization | DNA from decontaminated smear-negative sputum | 65.0 (58.0 to 71.0) | 96.0 (94.0 to 97.0) | |
Hain GT MTBDRplus | Hain Lifescience GbmH, Nehren, Germany | PCR amplification/hybridization | DNA from decontaminated sputum | 92.0 (90.0 to 94.0) | - |