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Table 4 The net reclassification improvement generated by employing different formulas using MDRD as a reference and a cutoff value of 60 mL/min/1.73 m 2

From: The glomerular filtration rate estimated by new and old equations as a predictor of important outcomes in elderly patients

Equation used

Outcome

NRI using a 60 mL/min cutoff

P

CKD-EPIcreat

Renal death

2%

0.08

Cardiovascular events

0%

0.49

Hospitalization

1%

0.13

No events

−2%

0.05

CKD-EPIcyst

Renal death

25%

<0.01

Cardiovascular events

7%

0.04

Hospitalization

3%

0.30

No events

1%

0.45

CKD-EPIcreatcyst

Renal death

18%

<0.01

Cardiovascular events

9%

0.03

Hospitalization

−2%

0.36

No events

0%

0.49

BIS

Renal death

−12%

0.01

Cardiovascular events

−2%

0.43

Hospitalization

−7%

0.07

No events

−7%

0.09

  1. Renal death (mortality or renal replacement therapy), severe cardiovascular events, hospitalization or absence of events over a three-year period were used as outcomes. NRI, net reclassification improvement.