Figure 2

Therapeutic treatment of established proteoglycan-induced arthritis (unpublished observations). Arthritic mice (n = 10 per treatment) were divided into two groups with similar mean severity scores and treated with 50 mg/kg anacardic acid or vehicle alone (control) for 12 days. Arrows indicate the days of treatment. The results shown are unpublished observations from original research conducted in our laboratory. Values are the mean ± standard error of the mean. ^* P <0.04; ^** P <0.01 ACA-treated versus vehicle-treated groups. ACA, anacardic acid; PGIA, proteoglycan-induced arthritis.