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Table 3 Quantitative gene (mRNA) expression data in ventricular samples from a background of no cardiac disease (Control), idiopathic cardiomyopathy (IDC) and ischemic cardiomyopathy (ICM).

From: ACE2 gene expression is up-regulated in the human failing heart

Target Copy number with 95% CI
  Control
(n = 9)
IDC
(n = 11)
Δ from
Control
ICM
(n = 12)
Δ from Control
ACE2 3,978
(2,102–5,531)
9,612†
(5,873–15,734)
2.4 7,338†
(5,304–10,153)
1.8
ACE 720
(349–1,484)
2,239†
(1,343–3,735)
3.1 1,692†
(1,295–2,211)
2.4
ANF 19,547
(4,377–87,287)
248,243†
(57,940–10,635,486)
12.7 151,551
(57,743–397,759)
7.8
AT 1 623
(456–850)
594
(347–1,020)
0.95 541
(352–829)
0.87
RENIN 0 0   0  
  1. Values are geometric mean copy number for each gene/100 ng total RNA. † – P < 0.05 disease group Vs. Control.