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Table 3 CNS DHA concentrations (mean ± SD, % w/w) for each treatment. One way Anova was significant (p < 0.05) for all structures except the spinal cord, internal capsule and medial geniculate. The right column shows the results of t tests. Gray matter falls into two classes: 1) LCP supplementation does not support DHA levels found for breastfed animals, detected for cerebral cortex and cerebellum; 2) LCP supplementation does support DHA levels, found in most other gray tissue (basal ganglia, limbic regions, thalamus and midbrain).

From: The influence of long chain polyunsaturate supplementation on docosahexaenoic acid and arachidonic acid in baboon neonate central nervous system

CNS Region

Group

Statistics

 

B

T+

T-

P+

P-

 

Gray,Class 1

      

Pre-Centralis

14.4 ± 0.9

12.6 ± 0.6

11.7 ± 1.0

13.0 ± 0.6

10.4 ± 0.7

[B>all; T+>P-; P+>T-,P-; T->P-]

Post-Centralis

14.1 ± 0.8

12.7 ± 0.8

11.7 ± 1.0

13.4 ± 0.6

10.4 ± 0.2

[B>T+,T-,P-; T+>T-,P-; P+>T-,P-; T->P-]

Occipital

13.9 ± 1.0

11.7 ± 0.9

10.7 ± 0.8

11.8 ± 0.1

8.7 ± 0.6

[B>all; T+>P+,P-; T->P+,P-; P+>P-]

Cingulate

13.4 ± 0.9

11.4 ± 0.7

10.7 ± 0.8

11.8 ± 0.8

9.5 ± 0.9

[B>all; T+>P-; P+>T-,P-; T->P-]

Frontal

12.7 ± 0.6

11.2 ± 0.8

10.6 ± 0.7

11.4 ± 0.4

8.4 ± 1.0

[B>all; T+>P+,P-; T->P-; P+>P-]

Temporal

12.2 ± 0.6

10.5 ± 1.1

10.3 ± 0.8

11.2 ± 0.5

9.0 ± 0.7

[B>all; T+,T-,P+>P-]

Cerebellum

12.6 ± 0.9

11.2 ± 0.7

10.6 ± 0.8

11.4 ± 0.2

7.7 ± 0.6

[B>all; T+>P-; T-,P+>P-]

Gray, Class 2

      

Globus Pallidus

15.8 ± 0.5

15.4 ± 0.6

12.7 ± 2.3

16.6 ± 0.3

13.4 ± 1.5

[B>T-,P-; T+>T-,P-; P+>T-,P-]

Putamen

14.7 ± 0.8

13.9 ± 0.9

13.5 ± 0.6

13.6 ± 1.3

11.6 ± 0.8

[B>T-,P-; T+,T-,P+>P-]

Caudate

14.3 ± 1.1

13.4 ± 0.8

13.0 ± 1.1

13.5 ± 0.8

11.3 ± 0.4

[B>T-,P-; T+,T-,P+>P-]

Superior Colliculus

15.2 ± 1.2

14.2 ± 1.1

13.6 ± 0.5

15.0 ± 0.4

13.4 ± 0.7

[B>T-,P-; P+>T-,P-]

Inferior Colliculus

14.4 ± 1.0

12.9 ± 1.4

13.4 ± 1.3

15.0 ± 0.6

13.4 ± 0.4

[B>T+; P+>T+,T-,P-]

Amygdala

12.0 ± 0.6

11.4 ± 0.6

10.8 ± 0.9

11.7 ± 0.5

9.4 ± 0.4

[B>T-,P-; T+,T-,P+>P-; P+>T-]

Hippocampus

13.0 ± 0.8

11.6 ± 0.5

10.6 ± 1.5

12.6 ± 0.5

9.0 ± 0.5

[B>T+,T-,P-; T+,T-,P+>P-; P+>T-]

Hypothalamus

12.0 ± 0.4

11.3 ± 0.6

11.0 ± 0.7

12.0 ± 0.8

10.6 ± 0.4

[B>T-,P-; T+>P-; P+>T-,P-]

Pulvinar

13.5 ± 0.6

12.7 ± 0.7

12.5 ± 1.0

14.6 ± 1.1

12.0 ± 0.4

[B>T-,P-; P+>all]

Thalamus DM

13.0 ± 1.0

12.4 ± 1.2

12.2 ± 0.9

13.5 ± 0.8

10.9 ± 1.3

[B>P-; T+,T-,P+>P-]

Thalamus VPL

12.9 ± 0.7

12.6 ± 0.9

12.2 ± 0.9

13.1 ± 1.7

10.3 ± 1.6

[B>P-; T+,T-,P+>P-]

Medial Geniculate

12.5 ± 1.3

12.8 ± 1.1

12.2 ± 0.9

12.6 ± 1.3

11.7 ± 0.8

 

Lateral Geniculate

11.2 ± 1.6

10.6 ± 0.9

9.5 ± 0.8

11.7 ± 0.7

8.8 ± 1.8

[B>T-,P-; T+>P-; P+>T-,P-]

White Matter

      

Corpus Callosum

7.0 ± 1.3

7.9 ± 0.7

6.4 ± 0.9

8.2 ± 0.7

6.3 ± 0.7

[T+>T-,P-; P+>B,T-,P-]

Internal Capsule

6.8 ± 1.0

7.0 ± 1.5

6.4 ± 0.7

7.9 ± 0.9

6.3 ± 1.4

 

Spinal Cord1

5.7 ± 0.3

6.0 ± 1.0

5.6 ± 0.5

6.2 ± 0.5

5.1 ± 0.6

 

Corona Radiation

5.5 ± 0.9

5.2 ± 0.9

4.4 ± 0.4

5.7 ± 0.8

4.7 ± 0.7

[B>T-; P+>T-,P-]

Optic Tract

4.8 ± 0.5

4.5 ± 0.4

4.3 ± 0.6

5.1 ± 0.3

3.9 ± 0.4

[B,T+>P-; P+>T+,T-,P-]

Optic Nerve

4.5 ± 0.5

4.0 ± 0.9

3.9 ± 0.4

4.8 ± 0.9

3.6 ± 0.3

[B>T-,P-; T+>P-; P+>all]

  1. 1Spinal cord is a mixture of white and gray matter.