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Table 5 Concentrations (mean ± SD) of selected fatty acids in three representative CNS regions. 18:0 (stearic acid) and 22:4n-6 (adrenic acid) were not significantly altered by treatments in these CNS regions or in most others. While 18:1n-9 (oleic acid) was significantly different in occipital cortex and hippocampus but not corpus callosum, the magnitude of the differences was small and overall means are reported. 22:5n-6 (Osbond acid) was significantly elevated in all regions (except thalamus DM), for the P- and T- groups, similar to the patterns shown for the regions in this table.

From: The influence of long chain polyunsaturate supplementation on docosahexaenoic acid and arachidonic acid in baboon neonate central nervous system

 

Occipital

Corpus Callosum

Hippocampus

   

18:0a

19.5 ± 0.23

18.4 ± 0.72

19.3 ± 0.40

   

18:1n-9

10.6 ± 0.30b1

15.9 ± 0.80

11.5 ± 0.30b2

   

22:4n-6c

5.60 ± 0.25

7.060 ± 0.29

5.89 ± 0.19

   

22:5n-6

B

T+

T-

P+

P-

 

Occipital

1.97 ± 0.23

2.26 ± 0.32

2.47 ± 0.40

1.85 ± 0.23

2.39 ± 0.16

T-,P->B; T+,T-,P->P+

Corpus Callosum

1.16 ± 0.22

1.79 ± 0.26

1.43 ± 0.27

1.41 ± 0.22

1.94 ± 0.33

T+,P->B; T->T+; T+>P+; P->T-,P+

Hippocampus

1.86 ± 0.30

2.27 ± 0.40

2.28 ± 0.41

1.88 ± 0.16

2.33 ± 0.14

T+,T-,P->B; T+,T-,P->P+

  1. a,cNo significant differences among groups (B, T+, T-, P+, P-).
  2. b1Significant group differences: B<T-,P+
  3. b2Significant group differences: B<T-,P+, P-