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Table 2 Reasons for discontinuation by study

From: Discontinuation of treatment of schizophrenic patients is driven by poor symptom response: a pooled post-hoc analysis of four atypical antipsychotic drugs

Reason for Discontinuation n (%)

Study 1 (n = 339)

Study 2 (n = 346)

Study 3 (n = 548)

Study 4 (n = 394)

Total (N = 1627)

Overall Discontinuation

161(47.5)

190(54.9)

268(48.9)

247(62.7)

866(53.2)

Poor Response or Worsening

67(41.6)

78(41.0)

99(36.9)

71(28.7)

315(36.4)

Intolerability to Medication

19(11.8)

16(8.4)

31(11.6)

40(16.2)

106(12.2)

Other Reasons*

75(46.6)

96(50.5)

138(51.5)

136(55.1)

445(51.4)

  1. *Other reasons for discontinuation included criteria not met, lost to follow-up, noncompliance, personal conflict, physician decision, satisfactory response, and sponsor decision.