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Table 5 Household contact prophylaxis with antiviral drugs, with or without treatment of the index cases. The interventions are applied in 70% of households in which one member consults a physician. Estimates are cumulative numbers per 100 inhabitants, unless otherwise specified.

From: A 'small-world-like' model for comparing interventions aimed at preventing and controlling influenza pandemics

Outcomes

Prophylaxis

(Outbreak, n = 90)

Prophylaxis + treatment

(Outbreak, n = 98)

 

Mean

Minimum-Maximum

Mean

Minimum-Maximum

Infections

    

   Total

36.1

32.1–40.1

34.2

30.8–37.4

Childrena

61.8

57.0–66.2

58.5

53.1–64.5

Adultsa

30.2

25.6–35.0

28.8

24.2–33.4

Elderlya

16.8

11.2–21.2

14.9

11.3–18.9

Physician visits

23.8

21.8–27.0

22.2

19.6–24.8

Hospital admissions

1.18

0.70–1.57

0.77

0.59–0.98

Deaths

0.25

0.13–0.43

0.16

0.06–0.28

Lost workdaysb

106

94–122

100

85–116

Treatment units (doses)c

196

179–210

393

356–435

  1. aPer 100 individuals of a given age
  2. bPer 100 working adults
  3. cTwo per day of treatment, five days per patient; one per day of prophylaxis, 10 days per person