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Figure 4 | BMC Medicine

Figure 4

From: Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model

Figure 4

Tissue specificity of macrophage invasion. Transcripts of markers specific for or consistent with the presence of macrophages in stria vascularis, spiral ligament, spleen and liver of Slc26a4 +/- and Slc26a4 -/- mice at P34 and/or P86 were quantified by qRT-PCR. Significant changes between Slc26a4 +/- and Slc26a4 -/- mice are marked with an asterisk (*). Numbers between bars represent the number of animal pairs analyzed. Note that significant increases were mainly seen in stria vascularis, to a lesser degree in spiral ligament, but not in spleen or liver. These data suggest that macrophage invasion is specific to stria vascularis.

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