Figure 5
From: Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model
Time course of macrophage invasion. Transcripts of markers specific for or consistent with the presence of macrophages in stria vascularis and spiral ligament of Slc26a4 +/- and Slc26a4 -/- mice at different ages were quantified by qRT-PCR to determine the time course of macrophage invasion during development. Significant changes between Slc26a4 +/- and Slc26a4 -/- mice are marked with an asterisk (*). Numbers between symbols represent the number of age-matched animal pairs analyzed. Note that significant differences were not seen before P34, suggesting that macrophage invasion occurred after weaning (P22).