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Table 4 Genes that were not expected to be expressed in stria vascularis.

From: Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model

   

Slc26a4 +/+

Slc26a4 -/-

  

No.

Gene

Description

Intensity

P

Intensity

P

Fold

Direction

1

Pres

Prestin

53

0/3

8

0/3

  

2

Kcnq4

K+ channel

160

0/6

160

0/6

  

3

Atp2b2

PMCA2

35

0/9

116

3/9

  

4

Calb1

Calbinin 28K

53

0/12

36

0/12

  

5

Calb2

Calretinin

28

0/3

27

0/3

  

6

Ache

Acetylcholinesterase

57

0/3

5

0/3

  

7

Slc1a3

Glutamate transporter GLAST

122

3/18

154

8/18

  

8

Gria1

Glutamate receptor, ionotropic

57

0/9

55

0/9

  

9

Atp6v1b1

H+ ATPase

58

0/3

26

0/3

  

10

Tecta

Tectorin, alpha

62

0/3

52

0/3

  

11

Tectb

Tectorin, beta

90

0/3

01

0/3

  

12

Otog

Otogelin

230

0/3

63

0/3

  

13

Otof

Otoferlin

231

0/3

214

0/3

  

14

Otop1

Otopetrin 1

54

0/3

62

1/3

  

15

Otop2

Otopetrin 2

247

0/3

203

0/3

  

16

Otop3

Otopetrin 3

60

0/3

47

0/3

  

17

Otos

Otospiralin

636

3/3

2,368

3/3

3.73

up

18

Slc4a7

Na+/HCO3 - cotransporter

398

3/3

444

3/3

1.11

 

19

Kcnj16

K+ channel

280

2/6

239

1/6

  
  1. Genes that are expected to be expressed in the organ of Corti, the modiolus or the vestibular labyrinth but not in stria vascularis (1–16), and genes that are expected to be expressed in spiral ligament but not in stria vascularis (17–19) are listed. For parameters 'P', 'Fold' and 'Direction', see the Gene array section in Methods. Fold changes are given when a gene was called Present (P) in Slc26a4 +/- or Slc26a4 -/- samples in at least half of the available probes. The direction of the fold change is only given when it exceeded 1.30. Fold changes lower than 1.30 were not considered significant.