Skip to main content

Table 5 Markers for macrophages/dendritic cells.

From: Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model

   

Slc26a4 +/+

Slc26a4 -/-

  

No.

Gene

Description

Intensity

P

Intensity

P

Fold

Direction

1

Ptprc

Cd45 antigen

226

3/3

946

3/3

4.19

up

2

Cd83

Cd83 antigen

126

0/3

524

3/3

4.16

up

3

Cd68

Cd68 antigen

170

3/3

1,344

3/3

7.90

up

4

Cd14

Cd14 antigen

412

1/3

619

3/3

1.50

up

5

H2-Aa

MHC class II

264

5/12

1,019

9/12

4.00

up

6

H2-Ab

MHC class II

126

0/9

279

3/9

1.86

up

7

H2-Eb1

MHC class II

429

0/3

1,010

3/3

2.35

up

8

Lgals3

Mac2 antigen

91

2/6

1,866

5/6

13.49

up

9

Itgax

Integrin alpha X

125

0/3

375

3/3

3.00

up

10

Emr1

Mucin receptor

750

3/3

1,547

3/3

2.06

up

11

Lyzs

Lysozyme

551

6/9

8257

9/9

11.78

up

12

H2-K1

MHC class I (D-region)

1,607

13/18

4,062

15/18

2.06

up

13

H2-K1

MHC class I (K-region)

1,828

6/12

2,883

6/12

1.54

up

14

H2-K1

MHC class I (Q-region)

549

1/3

890

3/3

1.62

up

15

C1r

Complement

37

2/6

266

6/6

13.87

up

16

C1s

Complement

71

0/3

200

1/3

  

17

C1qa

Complement

355

1/3

2,905

3/3

8.19

up

18

C1qb

Complement

552

5/6

2,001

6/6

4.43

up

19

C2

Complement

3,207

9/9

4,794

6/6

1.62

up

20

C3

Complement

11

0/3

231

2/3

20.68

up

21

C4

Complement

1,556

3/3

4,788

3/3

3.08

up

22

C3ar1

Complement receptor

177

3/9

482

6/9

2.93

up

23

Ctss

Cathepsin S

2,304

3/3

7,394

3/3

3.21

up

24

Ctsk

Cathepsin K

170

1/3

377

3/3

2.21

up

25

Ctsb

Cathepsin B

4,172

12/15

6,576

12/15

1.90

up

26

Msr2

Macrophage scavenger receptor

169

3/3

1140

3/3

6.75

up

27

Mpeg1

Macrophage expressed gene

582

0/3

5,527

3/3

9.49

up

28

Cst3

Cystatin C

5,562

3/3

8,652

3/3

1.56

up

29

Fcgr1

IgG receptor, high affinity

98

0/6

163

5/6

1.70

up

30

Fcgr2b

IgG receptor, low affinity

112

2/15

377

7/15

3.94

up

  1. Genes that can serve as markers macrophages/dendritic cells (1–10) and genes that are consistent with the presence of macrophages/dendritic cells (11–27) are listed. For parameters 'P', 'Fold' and 'Direction', see the Gene array section in Methods. Fold changes are given when a gene was called Present (P) in Slc26a4 +/- or Slc26a4 -/- samples in at least half of the available probes. The direction of the fold change is only given when it exceeded 1.30. Fold changes lower than 1.30 were not considered significant.