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Table 2 Serum alanine aminotransferase (ALT) measures (intent to treat analysis)

From: The effect of acetaminophen (four grams a day for three consecutive days) on hepatic tests in alcoholic patients – a multicenter randomized study

 

Serum ALT (IU/L)

 

Acetaminophen group

Placebo Group

p-value*

Day 0:

   

Mean ± SD

49 ± 38

47 ± 37

0.398

Range

4–189

8–175

 

n

308

135

 

Day 2:

   

Mean ± SD

45 ± 38

46 ± 34

0.949

Range

7–292

6–174

 

n

287

124

 

Day 3:

   

Mean ± SD

45 ± 36

50 ± 38

0.245

Range

7–230

6–242

 

n

274

118

 

Day 4:

   

Mean ± SD

48 ± 39

52 ± 43

0.411

Range

6–264

8–288

 

n

267

115

 

Day 5:

   

Mean ± SD

57 ± 45

55 ± 48

0.706

Range

7–312

7–282

 

n

261

114

 
  1. *Standardized values based upon upper limit of normal were used to calculate p-values.
  2. Normal ranges for CARES: ALT 5–40 IU/L male and 5–36 IU/L female. Two different labs were used by RCKC, normal ranges: ALT 0–50 IU/L and 2–60 IU/L male, 2–40 IU/L female.
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BMC Medicine

ISSN: 1741-7015

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