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Figure 4 | BMC Medicine

Figure 4

From: Upregulation of CRABP1 in human neuroblastoma cells overproducing the Alzheimer-typical Aβ42reduces their differentiation potential

Figure 4

CRABP1 was up-regulated specifically for an increased Aβ 42 /Aβ 40 ratio demonstrated by 2D-DIGE. Two-dimensional polyacrylamide gel electrophoresis of CyDye-labeled proteins, extracted from SH-SY5Y cells. C99I45F and C99V50F were compared with C99WT. Differentially expressed proteins, evaluated by intensity of merged colors (Cy5, Cy3), were identified by mass spectrometry. Arrows indicate CRABP1.

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