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Table 2 Disease characteristics of patients who underwent haematopoietic stem cell transplant (HSCT).

From: Safety and tolerability of the antimicrobial peptide human lactoferrin 1-11 (hLF1-11)

Patient no.

Age (years)

Gender

Diagnosis, stagea

Paraprotein type

Bence-Jones

Prior treatment

Statusb

Melphalan dose (mg/kg)

SC001

61

M

Multiple myeloma, III-A

IgG κ

Not present

VAD, CAD

Partial response

3.92

SC002

62

F

Multiple myeloma, III-A

IgG κ

Present

VAD, CAD

Progressive disease

5.61

SC003

50

M

Multiple myeloma, III-A

Light chain κ

Present

VAD, CAD

Minimal response

5.19

SC004

55

M

Multiple myeloma, III-A

IgG κ, light chain κ

Not present

VAD, CAD

Partial response

5.13

SC005

45

M

Multiple myeloma, III-A

Light chain κ

Present

PAD, CAD

Partial response

6.25

SC006

39

M

Multiple myeloma, III-B

IgG κ

Not present

VAD, CAD

Minimal response

4.37

SC007

54

M

Multiple myeloma, II-A

IgG κ

Not present

Thalidomide, dexamethasone, CAD

Stable disease

5.07

SC008

61

M

Lymphoplasmocytic lymphoma, IV-A

IgG κ, light chain κ

Present

VAD, CAD

Minimal response

5.13

  1. aStaging by Durie and Salmon criteria [41]; bstatus after previous treatment by International Bone Marrow Transplant Registry and Autologous Blood, and Marrow Transplant Registry criteria [42].
  2. ALT = alanine aminotransferase; AST = aspartate aminotransferase; CAD = cyclophosphamide, adriamycin, dexamethasone; PAD = bortezomib, adriamycin, dexamethasone; VAD = vincristine, adriamycin, dexamethasone.