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Table 6 DNMT3A -448A>G genotype and allele frequencies of case patients and control subjects and their association with oesophagus carcinoma (EC)

From: A functional polymorphism in the DNA methyltransferase-3A promoter modifies the susceptibility in gastric cancer but not in esophageal carcinoma

Genotype

EC (n= 96)

 

Control subjects (n= 241)

 

Crude odds ratio (95% confidence interval)

Pvalue*

 

No.

(%)

No.

(%)

  

- 448A>G

      

GG (ref.)

61

(63.5)

149

(61.8)

1.0

 

AG

28

(29.2)

86

(35.7)

0.795 (0.473-1.338)

0.388c

AA

7

(7.3)

6

(2.5)

2.850 (0.920-8.825)

0.115d

A allele

21.9

19.9

  
  1. *Chi-squared test;
  2. c versus GG genotype.
  3. d versus GG genotype.