Table 1 Proteins found in both African-American and Caucasian-American datasets reported to be involved in breast cancer, as annotated by Ingenuity Systems or BIOBASE.
Symbol | Entrez gene name | Location | Entrez gene ID |
|---|---|---|---|
ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | Plasma membrane | 10257 |
ACTA2 | Actin, alpha 2, smooth muscle, aorta | Cytoplasm | 59 |
ACTB | Actin, beta | Cytoplasm | 60 |
ADAMTS15 | ADAM metallopeptidase with thrombospondin type 1 motif, 15 | Extracellular space | 170689 |
ADRA1B | Adrenergic, alpha-1B-, receptor | Plasma membrane | 147 |
ANXA2 | Annexin A2 | Plasma membrane | 302 |
APOB | Apolipoprotein B (including Ag(x) antigen) | Extracellular space | 338 |
APOD | Apolipoprotein D | Extracellular space | 347 |
ATP5B | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide | Cytoplasm | 506 |
AXL | AXL receptor tyrosine kinase | Plasma membrane | 558 |
C3 | Complement component 3 | Extracellular space | 718 |
CAV1 | Caveolin 1, caveolae protein, 22 kDa | Plasma membrane | 857 |
CNR2 | Cannabinoid receptor 2 (macrophage) | Plasma membrane | 1269 |
COL18A1 | Collagen, type XVIII, alpha 1 | Extracellular space | 80781 |
CYP2C9 | Cytochrome P450, family 2, subfamily C, polypeptide 9 | Cytoplasm | 1559 |
DCD | Dermcidin | Extracellular space | 117159 |
DSP | Desmoplakin | Plasma membrane | 1832 |
FES | Feline sarcoma oncogene | Cytoplasm | 2242 |
FN1 | Fibronectin 1 | Plasma membrane | 2335 |
GART | Phosphoribosylglycinamide formyltransferase/synthetase, | Cytoplasm | 2618 |
GFRA1 | GDNF family receptor alpha 1 | Plasma membrane | 2674 |
HSPA5 | Heat shock 70 kDa protein 5 (glucose-regulated protein, 78 kDa) | Cytoplasm | 3309 |
HSPG2 | Heparan sulfate proteoglycan 2 | Plasma membrane | 3339 |
IGF2R | Insulin-like growth factor 2 receptor | Plasma membrane | 3482 |
IGKC | Immunoglobulin kappa constant | Extracellular space | 3514 |
ITGA2 | Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | Plasma membrane | 3673 |
JUP | Junction plakoglobin | Plasma membrane | 3728 |
LAMA3 | Laminin, alpha 3 | Extracellular space | 3909 |
LDHA | Lactate dehydrogenase A | Cytoplasm | 3939 |
LEPR | Leptin receptor | Plasma membrane | 3953 |
LGALS1 | Lectin, galactoside-binding, soluble, 1 | Extracellular space | 3956 |
MAGED1 | Melanoma antigen family D, 1 | Plasma membrane | 9500 |
MAP3K4 | Mitogen-activated protein kinase kinase kinase 4 | Cytoplasm | 4216 |
MUC16 | Mucin 16, cell surface associated | Extracellular space | 94025 |
MUC5AC | Mucin 5AC, oligomeric mucus/gel-forming | Extracellular space | 4586 |
NF1 | Neurofibromin 1 | Cytoplasm | 4763 |
PCM1 | Pericentriolar material 1 | Cytoplasm | 5108 |
POSTN | Periostin, osteoblast specific factor | Extracellular space | 10631 |
PRDX3 | Peroxiredoxin 3 | Cytoplasm | 10935 |
PRKCG | Protein kinase C, gamma | Cytoplasm | 5582 |
PRLR | Prolactin receptor | Plasma membrane | 5618 |
PTN | Pleiotrophin | Extracellular space | 5764 |
PTPN13 | Protein tyrosine phosphatase, non-receptor type 13 | Cytoplasm | 5783 |
PXDN | Peroxidasin homolog (Drosophila) | Unknown | 7837 |
SERPINA1 | Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin) 1 | Extracellular space | 5265 |
SLC16A3 | Solute carrier family 16, member 3 (monocarboxylic acid transporter 4) | Plasma membrane | 9123 |
SLC19A1 | Solute carrier family 19 (folate transporter), member 1 | Plasma membrane | 6573 |
TES | Testis derived transcript (3 LIM domains) | Plasma membrane | 26136 |
TNC | Tenascin C | Extracellular space | 3371 |
TUBA1A | Tubulin, alpha 1a | Cytoplasm | 7846 |
VCL | Vinculin | Plasma membrane | 7414 |
VTN | Vitronectin | Extracellular space | 7448 |