Table 3 Proteins found unique to the Caucasian-American dataset that are reported to be involved in breast cancer, as annotated by Ingenuity Systems or BIOBASE.
Symbol | Entrez gene name | Location | Entrez gene ID |
|---|---|---|---|
ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | Plasma membrane | 10057 |
ACE | Angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | Plasma membrane | 1636 |
BCAR3 | Breast cancer anti-estrogen resistance 3 | Cytoplasm | 8412 |
CDON | Cdon homolog (mouse) | Plasma membrane | 50937 |
CLCA2 | CLCA family member 2, chloride channel regulator | Plasma membrane | 9635 |
CSF1R | Colony stimulating factor 1 receptor | Plasma membrane | 1436 |
CTGF | Connective tissue growth factor | Extracellular space | 1490 |
DAPK1 | Death-associated protein kinase 1 | Cytoplasm | 1612 |
DLG5 | Discs, large homolog 5 (Drosophila) | Plasma membrane | 9231 |
ERBB3 | V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | Plasma membrane | 2065 |
FRZB | Frizzled-related protein | Extracellular space | 2487 |
GREB1 | GREB1 protein | Cytoplasm | 9687 |
HGF | Hepatocyte growth factor (hepapoietin A; scatter factor) | Extracellular space | 3082 |
HPN | Hepsin (transmembrane protease, serine 1) | Plasma membrane | 3249 |
HSPA8 | Heat shock 70 kDa protein 8 | Cytoplasm | 3312 |
IL17RB | Interleukin 17 receptor B | Plasma membrane | 55540 |
IRS2 | Insulin receptor substrate 2 | Cytoplasm | 8660 |
ITGA6 | Integrin, alpha 6 | Plasma membrane | 3655 |
KCNH1 | Potassium voltage-gated channel, subfamily H (eag-related), member 1 | Plasma membrane | 3756 |
KISS1 | KiSS-1 metastasis-suppressor | Cytoplasm | 3814 |
LGALS3 | Lectin, galactoside-binding, soluble, 3 | Extracellular space | 3958 |
LPA | Lipoprotein, Lp(a) | Extracellular space | 4018 |
LPHN2 | Latrophilin 2 | Plasma membrane | 23266 |
LTA | Lymphotoxin alpha (TNF superfamily, member 1) | Extracellular space | 4049 |
MAP2K5 | Mitogen-activated protein kinase kinase 5 | Cytoplasm | 5607 |
MINK1 | Misshapen-like kinase 1 (zebrafish) | Cytoplasm | 50488 |
NOS3 | Nitric oxide synthase 3 (endothelial cell) | Cytoplasm | 4846 |
NOTCH4 | Notch homolog 4 (Drosophila) | Plasma membrane | 4855 |
NRG1 | Neuregulin 1 | Extracellular space | 3084 |
OAS3 | 2'-5'-oligoadenylate synthetase 3, 100 kDa | Cytoplasm | 4940 |
P4HB | Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide | Cytoplasm | 5034 |
PKD1 | Polycystic kidney disease 1 (autosomal dominant) | Plasma membrane | 5310 |
PLG | Plasminogen | Extracellular space | 5340 |
PTPRF | Protein tyrosine phosphatase, receptor type, F | Plasma membrane | 5792 |
RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | Cytoplasm | 5921 |
SERPINI2 | Serpin peptidase inhibitor, clade I (pancpin), member 2 | Extracellular space | 5276 |
SH3RF1 | SH3 domain containing ring finger 1 | Cytoplasm | 57630 |
SOCS1 | Suppressor of cytokine signaling 1 | Cytoplasm | 8651 |
TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | Plasma membrane | 23158 |
TGFBR2 | Transforming growth factor, beta receptor II (70/80 kDa) | Plasma membrane | 7048 |
TIAM1 | T-cell lymphoma invasion and metastasis 1 | Cytoplasm | 7074 |
TNN | Tenascin N | Plasma membrane | 63923 |
TPI1 | Triosephosphate isomerase 1 | Cytoplasm | 7167 |
VWF | von Willebrand factor | Extracellular space | 7450 |
WISP2 | WNT1 inducible signaling pathway protein 2 | Extracellular space | 8839 |
WNT11 | Wingless-type MMTV integration site family, member 11 | Extracellular space | 7481 |
YWHAZ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | Cytoplasm | 7534 |