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Table 1 Structure of families included in the study.

From: An evaluation of inflammatory gene polymorphisms in sibships discordant for premature coronary artery disease: the GRACE-IMMUNE study

No. of affecteds

No. of unaffecteds

No. of families with

  

CAD

CAD before 50 years*

MI †

1

1

164

149

122

1

2

439

235

362

1

>2

49

38

39

2

1

158

46

78

2

2

42

15

23

2

>2

18

6

14

≥ 3

≥1

21

4

11

Total families

 

891

493

660

Total affecteds

 

1154

568

802

Total unaffecteds

 

1545

855

1204

  1. * In this setting, individuals affected after 50 years were considered as unphenotyped
  2. † For this trait coding, individuals free of myocardial infarction (MI) but affected by other forms of coronary artery disease (CAD) were considered unphenotyped.