Table 1 Baseline characteristics of the low excretor population, by treatment outcome(s): age, sex, race, height, weight, BMI and medication use.
| Â | Â | Â | All | First randomization | Second randomization | ||
|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | PRM | Placebo | PRM | Placebo |
| Â | Â | N | 172 | 86 | 86 | 127 | 39 |
Characteristic | Visit | Â | Â | Â | Â | Â | Â |
Age (years) | 1 | Mean (SD) | 63.8 (9.3) | 63.4 (9.8) | 64.2 (8.8) | 63.4 (9.6) | 64.3 (8.3) |
Sex | Â | N (%) female | 128 (74.4%) | 63 (73.3%) | 65 (75.6%) | 96 (75.6%) | 28 (71.8%) |
Race* | Â | N (%) white | 170 (98.8%) | 84 (97.7%) | 86 (100.0%) | 125 (98.4%) | 39 (100.0%) |
Height (m) | 1 | Mean (SD) | 1.63 (0.08) | 1.64 (0.09) | 1.63 (0.08) | 1.64 (0.09) | 1.62 (0.08) |
Weight (kg) | 1 | Mean (SD) | 71.4 (13.1) | 71.0 (14.0) | 71.8 (12.2) | 70.9 (13.4) | 72.8 (12.3) |
BMI (kg/m2) | 1 | Mean (SD) | 26.7 (4.1) | 26.4 (3.9) | 27.1 (4.3) | 26.4 (4.0) | 27.7 (4.5) |
Taking any medications | 1 | N (%) | 17 (9.9%) | 6 (7.0%) | 11 (12.8%) | 10 (7.9%) | 6 (15.4%) |
Taking codeine†| 1 | N (%) | 29 (16.9%) | 13 (15.1%) | 16 (18.6%) | 21 (16.5%) | 8 (20.5%) |
Taking codeine | 2 | N (%) | 26 (15.1%) | 16 (18.6%) | 10 (11.6%) | 21 (16.5%) | 5 (12.8%) |
Confirmed codeine analgesic | 2 | N (%) | 15 (8.7%) | 8 (9.3%) | 7 (8.1%) | 11 (8.7%) | 4 (10.3%) |