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Table 1 Sensitivity, specificity, positive/negative predictive values, positive/negative likelihood ratios for major depression

From: The 'help' question doesn't help when screening for major depression: external validation of the three-question screening test for primary care patients managed for physical complaints

Parameter

Two screening questions

% (95% CI)

Three screening questions

% (95% CI)

Sensitivity

91.3% (81.4 to 96.4)

59.4% (47.0 to 70.9)

Specificity

65.0% (61.2 to 68.6)

88.2% (85.4 to 90.5)

Positive predictive value

21.6% (17.1 to 26.8)

34.7% (26.4 to 44.1)

Negative predictive value

98.6% (96.8 to 99.4)

95.3% (93.3 to 96.8)

Positive likelihood ratio

2.6 (2.3 to 3.0)

5.0 (3.8 to 6.7)

Negative likelihood ratio

0.1 (0.06 to 0.28)

0.5 (0.3 to 0.6)