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Table 2 GSEA results for nine biological systems, comparing AA versus CA.*

From: Differential endothelial cell gene expression by African Americans versusCaucasian Americans: a possible contribution to health disparity in vascular disease and cancer

Biological System

Gene Set Size

Nominal P

FDR

Adhesion

146

0.907

.100

Angiogenesis

131

0.960

.946

Apoptosis

79

0.202

.551

Coagulation

152

0.416

.815

Hypoxia

104

0.547

.780

Inflammation

117

0.989

.987

Redox

83

0.788

.932

Shear stress

156

0.027

.140

Vasoregulation

101

0.822

.920

  1. * For GSEA (Gene Set Enrichment Analysis), FDR <.25 is considered to be significant (see Methods). Construction and specific composition of gene sets has been presented elsewhere [37, 49].