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Table 3 Shear Stress Biological Gene Set (156 Members)

From: Differential endothelial cell gene expression by African Americans versusCaucasian Americans: a possible contribution to health disparity in vascular disease and cancer

Gene Contributes to Core Enrichment

Gene Does Not Contribute to Core Enrichment

BMP4

SP1

ACTB

GJA1

PDPK1

BMP6

TBXAS1

AKAP1

GNAS

PECAM1

CCL2

TGFB1

ANXA2

GNB2

PFDN5

CD34

THBD

ANXA5

GNG5

PTGS2

CENPF

THBS1

APOE

GRN

RGS5

CTGF

TRA1

APS

HADHSC

RPL30

CXCL12

TUBG1

ARF4L

HMOX1

RPL34

CYP1B1

VCAM1

ASS

ICAM1

RPS11

CYR61

VIPR1

CAV1

IFITM3

RPS7

DPYSL3

XPO1

CCL15

IL13RA1

SAT

EDN1

 

CCL25

IL15

SCGF

EEF1A2

 

CD164

IL16

SELE

ELN

 

CD1D

IL1R1

SERPINE1

F3

 

CD58

IL1RL1

SERPINE2

FGF2

 

CD68

ITGB3

SLC35F2

FN1

 

CDKN1A

JARID1A

SMARCD1

GAPD

 

CEACAM1

JUN

SOD2

GBP1

 

CYP1A1

KLF2

SPARC

GJA5

 

DKK2

LAMB1

SPTA1

GSTP1

 

E2F5

LIMS1

SPTAN1

IL8

 

EDN3

LRP2

STAM

ILK

 

EFEMP1

METAP2

TEK

JAG2

 

EGR1

MGP

TFPI

JUNB

 

EIF4EBP2

MMP1

TGFB1I4

KIF20A

 

EIF4G3

MMP14

THBS4

KLF4

 

ESM1

MMRN1

TNFRSF1A

LIG3

 

F2

MYD88

TNFRSF5

MAPRE1

 

F2R

NFKB1

TNFSF8

MATN2

 

FGF6

NOTCH4

TUBA3

MYC

 

FGFR3

NQO1

TXNRD1

NOS3

 

FLT1

NUMA1

UNG

PFDN2

 

FOS

OGT

VCL

PLAT

 

FOSL1

OLR1

VEGFC

RGS3

 

FTH1

PBP

VWF

RHOA

 

FTL

PCQAP

WNT2B

RHOB

 

GARS

PDGFRA

 

S100A10

 

GAS

PDGFRB

 
  1. "Core enrichment" indicates that the corresponding gene is in the subset of genes that contributes most significantly to that biological system's result using GSEA (Table 2) in the text. In the table above, entries are listed in alphabetical order. An expanded version of these gene names is available as Additional File 5.