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Figure 1 | BMC Medicine

Figure 1

From: MIA is a potential biomarker for tumour load in neurofibromatosis type 1

Figure 1

Elevated expression of cd-rap/Mia in the Nf1 -deficient cartilage. (A) In situ hybridization of the melanoma-inhibitory activity/cd-rap (mia)-specific riboprobe on the transverse sections of E14.5 Nf1Prx1 embryos. Intensity of staining reflects abundance of Mia transcript. (B) Quantitative real-time polymerase chain reaction (qRT-PCR) of Mia transcript in the postnatal day 4 knee joints. Data represent means (± SD) of duplicate absolute quantifications for each probe. Transcript of the housekeeping gene glyceraldehyde 3-phosphate dehydrogenase (GAPDH) was used as control.

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