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Table 5 Clinical-biochemical characteristics of study population according to serum 25(OH) vitamin D quartiles.

From: Strong association between non alcoholic fatty liver disease (NAFLD) and low 25(OH) vitamin D levels in an adult population with normal serum liver enzymes

 

I Quartile

(n = 51)

II Quartile

(n = 66)

III Quartile

(n = 62)

IV Quartile

(n = 83)

P-value

Age (years)

55.93 ± 9.34

52.1 ± 10.7

52.2 ± 11.2

52.24 ± 9.45

n.s.

Sex° (M/F)

30/21

32/34

33/29

37/46

n.s.

BMI (kg/m2)

30.99 ± 6.96

29.5 ± 5.8

27.04 ± 4

26.25 ± 4.38

< 0.001

Waist circumference (cm)

105.27 ± 16.82

103.6 ± 14.8

95.01 ± 19.2

91.08 ± 16.72

0.001

FBG (mg/dl)

111.5 ± 26.1

106.3 ± 23.7

107.7 ± 30.2

103.2 ± 31.1

n.s.

Total cholesterol (mg/dl)

206.05 ± 49.46

201.3 ± 41.1

197.5 ± 35.8

192.07 ± 40.95

n.s.

LDL-cholesterol (mg/dl)

122.73 ± 44.62

126.8 ± 37.5

123.6 ± 33.2

109.15 ± 46.07

n.s.

HDL-cholesterol (mg/dl)

51.88 ± 16.36

52.5 ± 12.7

52.5 ± 12.2

52.71 ± 13.82

n.s.

Triglycerides (mg/dl)

178.8 ± 98.7

124.8 ± 84.7

124.6 ± 75

115.6 ± 60.8

0.001

HOMA-IR

10.01 ± 7.58

5.15 ± 4.3

4.3 ± 9.8

5.32 ± 7.86

0.03

AST (IU/l)

21.1 ± 7.4

22.1 ± 11.1

25.6 ± 10.7

21.8 ± 11.01

n.s.

ALT (IU/l)

25.5 ± 14

28.8 ± 16.6

28.6 ± 21.7

26.7 ± 19.2

n.s.

FLI

71.77 ± 26.83

51.9 ± 33.3

45.02 ± 35.9

32.04 ± 29.79

< 0.001

NAFLD ° (%)

68.3

56.1

50

37.3

0.01

MS ° (%)

72.5

43.9

35.5

33.3

< 0.001

T2D ° (%)

36.2

22.7

24.2

25.3

n.s.

  1. Results are shown as mean ± SD. ANOVA test applied. Kruskal-Wallis test applied. HOMA-IR, FBG, triglycerides, AST and ALT were considered as log-values in the analysis. P-values < 0.05 were considered significant.
  2. BMI, body mass index; FBG, fasting blood glucose; LDL, low-density lipoprotein; HDL, high density lipoprotein; HOMA-IR, homeostatis model assessment of insulin resistance; AST, aspartate aminotransferase; ALT, alanine aminotransferase; FLI, fatty liver index; NAFLD, non-alcoholic fatty liver disease; MS, metabolic syndrome; T2D, type 2 diabetes.