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Figure 4 | BMC Medicine

Figure 4

From: Ancestral exposure to stress epigenetically programs preterm birth risk and adverse maternal and newborn outcomes

Figure 4

Ancestral stress alters brain miRNA expression. (A) Heat map of miRNA expression modulated by multigenerational stress in brains of F2-SSS dams. (B) Confirmation of miRNA level changes in brains of F0-S and F2-SSS compared to non-stress F0-N rats by qRT-PCR. Ancestral programming by stress particularly involved the miR-200 family. Sno202, U6 and 5 s rRNA were used as references. Asterisks indicate significances: *P <0.05; **P <0.01, compared to F0-S levels.

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BMC Medicine

ISSN: 1741-7015

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