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Table 4 Multivariable logistic regression models for association between HIV status and hypertension to assess for confounding

From: Hypertension, kidney disease, HIV and antiretroviral therapy among Tanzanian adults: a cross-sectional study

Model

Controls (number = 153)

HIV-infected, ART naive

P-value versus control

HIV-infected, on ART

P-value versus control

Likelihood ratio test (compared to unadjusted model)

(number = 151)

(number = 150)

1) Unadjusted

1

0.28 [0.12 to 0.66]

0.003

2.06 [1.18 to 3.59]

0.01

0

2) Adjusted for age + sex

1

0.32 [0.14 to 0.75]

0.009

2.13 [1.18 to 3.85]

0.01

21.7, 2 d.f.

3) Adjusted for age + sex + body mass index (BMI)

1

0.34 [0.14 to 0.79]

0.01

2.04 [1.12 to 3.67]

0.02

25.7, 3 d.f.

4) Adjusted for age + sex + waist-hip ratio (WHR)

1

0.31 [0.13 to 0.73]

0.007

2.04 [1.12 to 3.71]

0.02

22.2, 3 d.f.

5) Adjusted for age + sex + BMI + vigorous work + alcohol

1

0.35 [0.15 to 0.84]

0.02

2.19 [1.18 to 4.05]

0.01

37.7, 5 d.f. a

6) Adjusted for age + sex + WHR + vigorous work + alcohol

1

0.32 [0.14 to 0.77]

0.01

2.19 [1.17 to 4.10]

0.01

35.4, 5 d.f.

  1. aBest fit model. All models are comparing to HIV-negative controls. Models 1, 2, 3 and 4 were predetermined based on most likely confounders. Models 5 + 6 included other baseline characteristics significantly associated with hypertension in the minimally-adjusted model. ART, antiretroviral therapy.