Outcome | Comparison | Number of studies | MD or RR (95% CI) | P | I 2 |
---|---|---|---|---|---|
Length of ICU stay (d) | EGDT versus control group | 6 | -0.20 (-1.31 to 0.92) | 0.73 | 75% |
Length of in-hospital stay (d) | EGDT versus control group | 4 | 0.42 (-1.02 to 1.86) | 0.57 | 12% |
Mechanical ventilation rate | EGDT versus control group | 5 | 0.96 (0.85 to 1.09) | 0.53 | 43% |
Mechanical ventilation days (d) | EGDT versus control group | 4 | -0.91 (-2.34 to 0.52) | 0.21 | 95% |
Vasopressor support rate | EGDT versus control group | 6 | 1.03 (0.93 to 1.15) | 0.58 | 69% |
Inotropic agents support | EGDT versus control group | 5 | 2.23 (1.06 to 4.67) | 0.03 | 84% |
EGDT versus usual care group | 4 | 2.37 (1.02 to 5.51) | 0.05 | Â | |
EGDT versus early lactate clearance | 1 | 1.60 (0.54 to 4.78) | 0.40 | 88%- | |
Fluid administration in first 6Â h (L) | EGDT versus control group | 7 | 0.88 (-0.17 to 1.93) | 0.10 | 99% |
EGDT versus usual care group | 5 | 1.24 (0 to 2.48) | 0.05 | 99% | |
EGDT versus early lactate clearance | 2 | 0.02 (-0.46 to 0.49) | 0.27 | 17% | |
Red cell transfusion rate in first 6Â h | EGDT versus control group | 5 | 1.76 (1.11 to 2.78) | 0.04 | 76% |
EGDT versus usual care group | 3 | 2.26 (1.54 to 3.31) | <0.01 | 71% | |
EGDT versus early lactate clearance | 2 | 0.72 (0.27 to 1.94) | 0.52 | 37% |