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Table 3 Accuracy characteristics of microRNAs in discriminating metastatic and non-metastatic lymph nodes in FFPE and FNA biopsies from lymph node samples

From: Erratum: Accuracy of microRNAs as markers for the detection of neck lymph node metastases in patients with head and neck squamous cell carcinoma

microRNA

PPV

NPV

Accuracy

AUC (95 % CI)

% (95 % CI)

% (95 % CI)

% (95 % CI)

FFPE samples

 miR-200a

100 (82.2-100.0)

68.4 (43.5-87.3)

84.2 (68.1-93.4)

0.92 (0.83-0.99)

 miR-200c

100 (84.4-100.0)

81.2 (54.34-95.73)

92.1 (77.5-97.9)

0.94 (0.85-1.0)

 miR-203

100 (86.2-100)

100 (75.1-100)

100 (88.6-100)

1.0 (0–1.0)

 miR-205

100 (86.2-100)

100 (75.1-100)

100 (88.6-100)

1.0 (0–1.0)

FNA samples classified by cytology

 miR-203

100 (91.5-100)

100 (94.9-100)

100 (96.05-100)

1.0 (0–1.0)

 miR-205

100 (91.5-100)

100 (94.9-100)

100 (96.05-100)

1.0 (0–1.0)

FNA samples classified by histology

 miR-203

100 (90.9-100)

95.9 (88.6-99.1)

97.3 (92.1-99.4)

0.963 (0.921-1.0)

 miR-205

100 (93.2-100)

94.6 (85.1-98.8)

96.7 (93.1-100)

0.966 (0.921-1.0)

  1. FFPE, formalin-fixed paraffin embedded; FNA, fine-needle aspiration; PPV, positive predictive value; NPV, negative predictive value; AUC, area under the ROC curve; CI, confidence interval