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Fig. 7 | BMC Medicine

Fig. 7

From: The public health impact of malaria vaccine RTS,S in malaria endemic Africa: country-specific predictions using 18 month follow-up Phase III data and simulation models

Fig. 7

Predicted cumulative direct deaths averted per 100,000 fully vaccinated over 10 years for sub-Saharan Africa for each of the four vaccine implementations: EPI, EPI with boosters, extended routine and extended routine with boosters. Predictions of the overall number of direct malaria deaths averted per 100,000 fully vaccinated over ten years, for vaccine and coverage sensitivities B-G (see Table 3), for EPI (red), EPI with boosters (orange), extended routine (dark blue), and extended routine with booster (light blue). Points correspond to the means of the predictions based on weighted averages over all simulations of the vaccine profile. Vertical lines correspond to the means of the predictions for the reference vaccine profile for each of the four vaccination schedules. Error bars represent the minima and maxima of the predictions based on replication of the simulations with 6 different model variants each with 5 random number seeds

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