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Table 2 Diagnostic performance of troponin I measured upon admission in the validation cohort

From: Identification of acute myocardial infarction in patients with atrial fibrillation and chest pain with a contemporary sensitive troponin I assay

Troponin I threshold optimized for

Cut-off

Sensitivity

Specificity

PPV

NPV

[ng/mL]

(95% CI)

(95% CI)

(95% CI)

(95% CI)

Sensitivity

0.019

0.90 (0.80-0.96)

0.88 (0.84-0.92)

0.66 (0.55-0.76)

0.97 (0.94-0.99)

Specificity

0.09

0.69 (0.56-0.80)

0.98 (0.95-0.99)

0.88 (0.75-0.95)

0.93 (0.89-0.96)

Unweighted

0.04

0.82 (0.70-0.91)

0.92 (0.88-0.95)

0.73 (0.61-0.83)

0.95 (0.92-0.98)

99th percentile threshold

0.032

0.85 (0.74-0.93)

0.91 (0.87-0.94)

0.71 (0.59-0.81)

0.96 (0.93-0.98)

  1. Cut-offs applied are derived from the derivation cohort optimized with respect to high sensitivity and high specificity or are unweighted compared with the 99th percentile cut-off of the assay used. 95 % CI denotes 95 % confidence interval