Cut-off | Sensitivity | Specificity | PPV | NPV | |
---|---|---|---|---|---|
[ng/mL] | (95 % CI) | (95 % CI) | (95 % CI) | (95 % CI) | |
Absolute 3-h change in troponin I concentration | |||||
n=298, n=54 patients with MI type 1 | |||||
Absolute 3-h change threshold optimized for: | |||||
Sum of sensitivity and specificity | 0.011 | 0.83 (0.71-0.92) | 0.90 (0.85-0.93) | 0.64 (0.52-0.75) | 0.96 (0.93-0.98) |
Specificity | 0.023 | 0.81 (0.69-0.91) | 0.94 (0.91-0.97) | 0.76 (0.63-0.86) | 0.96 (0.92-0.98) |
Absolute 3-h change in troponin I concentration and troponin I on admission above 99th percentile cut-off | |||||
n=66, n=46 patients with MI type 1 | |||||
Absolute 3-h change threshold optimized for: | |||||
Sum of sensitivity and specificity | 0.011 | 0.80 (0.66-0.91) | 0.55 (0.32-0.77) | 0.80 (0.66-0.91) | 0.55 (0.32-0.77) |
Specificity | 0.023 | 0.80 (0.66-0.91) | 0.70 (0.46-0.88) | 0.86 (0.72-0.95) | 0.61 (0.39-0.80) |
Absolute 3-h change in troponin I concentration and troponin I on admission above unweighted optimized cut-off | |||||
n=61, n=44 patients with MI type 1 | |||||
Absolute 3-h change threshold optimized for: | |||||
Sum of sensitivity and specificity | 0.011 | 0.80 (0.65-0.90) | 0.65 (0.38-0.86) | 0.85 (0.71-0.94) | 0.55 (0.32-0.77) |
Specificity | 0.023 | 0.80 (0.65-0.90) | 0.82 (0.57-0.96) | 0.92 (0.79-0.98) | 0.61 (0.39-0.80) |
Absolute 3-h change in troponin I concentration and troponin I on admission above specificity-optimized cut-off | |||||
n=41, n=36 patients with MI type 1 | |||||
Absolute 3-h change threshold optimized for | |||||
Sum of sensitivity and specificity | 0.011 | 0.75 (0.58-0.88) | 0.80 (0.28-0.99) | 0.96 (0.82-1) | 0.31 (0.09-0.61) |
Specificity | 0.023 | 0.75 (0.58-0.88) | 0.80 (0.28-0.99) | 0.96 (0.82-1) | 0.31 (0.09-0.61) |