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Fig. 2 | BMC Medicine

Fig. 2

From: Constitutive phosphorylated STAT3-associated gene signature is predictive for trastuzumab resistance in primary HER2-positive breast cancer

Fig. 2

The pSTAT3-GS has predictive significance in the independent randomized FinHer dataset. a–i Kaplan–Meier curves and forest plots of signature status assessed in the FinHer dataset. Patients with pSTAT3-GS low (a, d, g) and pSTAT3-GS high (b, e, h) status according to trastuzumab treatment in all patients (up), ER-negative only (middle), or ER-positive only (down). Forest plots according to pSTAT3-GS status in all patients (c), ER- negative only (f), or ER-positive only (i). The plots indicate Cox regression hazard ratios and 95 % confidence intervals for trastuzumab benefit for DDFS

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BMC Medicine

ISSN: 1741-7015

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