From: Progress in adjuvant chemotherapy for breast cancer: an overview
Breast cancer subtype/classification | Adjuvant systemic therapy | ||||
---|---|---|---|---|---|
Phenotypic subtype | Intrinsic subtype | Endocrine therapy | Anti-HER2 therapy | Chemotherapy | |
Hormone receptors | HER2 overexpression | Â | Â | Â | Â |
+ | – | Luminal A or B | Yes | No | Yes (if high risk) |
+ | + | Luminal B or HER2 enriched | Yes | Yes | Yes |
– | – | Basal | No | No | Yes |
– | + | HER2 enriched | No | Yes | Yes |