Fig. 5

Relapse attack among groups during year after therapy. Relapse timing and extent among treatment groups (AS + PQ, solid black; AS-PYR + PQ, black dashed; DHA-PP + PQ, black dotted) in the current trial. The upper solid red line (AS) represents the relapse control group used as the denominator in estimating efficacy, taken from a prior trial in soldiers deployed to the same region [7]. The other upper red line that is dashed (ACT only) represents relapse events among 39 soldiers with vivax malaria at Sragen who declined participation and were treated with DHA-PP but without primaquine. AS artesunate, PQ primaquine, PYR pyronaridine, DHA-PP dihydroartemisinin-piperaquin