High oxidative stress by | Proportion of population | ncases
| RR (95 % CI)c
|
---|
d-ROMsa
| TTLb
| ESTHER | HAPIEE controls | ESTHER + HAPIEE | ESTHER + HAPIEE |
---|
No | No | 59 % | 49 % | 227 | Ref |
No | Yes | 18 % | 25 % | 108 | 1.34 (0.91–1.97) |
Yes | No | 16 % | 18 % | 155 | 1.72 (1.27–2.32)* |
Yes | Yes | 7 % | 9 % | 70 | 2.47 (1.58–3.98)* |
- *Statistically significant (P <0.05)
-
ad-ROMs levels >400 Carr U
-
bLowest quartile of TTL in the different cohorts, i.e. ESTHER <281.57 μmol/L; HAPIEE Poland cases and eligible controls <464 μmol/L; HAPIEE Czech Republic cases and eligible controls <371 μmol/L; HAPIEE Lithuania cases and eligible controls <283 μmol/L
-
cMeta-analysis of HAPIEE Poland, Czech Republic, Lithuania and ESTHER study. Model controlled for age, sex, education, BMI, smoking status, alcohol consumption and vigorous physical activity
- CI, Confidence interval; ncases, Incident case numbers; RR, Risk ratio