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Table 3 Incidence of invasive meningococcal disease (IMD) in adults and relative risk by HIV status and capsular group in England during 2011–2013

From: Risk of invasive meningococcal disease in children and adults with HIV in England: a population-based cohort study

  

Incidence of meningococcal

   

Capsular group

Age group (years)

Persons co-infected with HIV

Uninfected persons

Rate ratio

95 % CI

P value

All

All

6.6

1.4

4.5

(2.7, 7.7)

<0.001

 

16–24

44.8

1.7

26.8

(8.7, 82.8)

<0.001

 

25–44

4.4

0.4

11.9

(5.0, 28.2)

<0.001

 

45–64

5.9

0.6

10.5

(4.4, 25.1)

<0.001

ACYW

All

4.7

0.3

16.0

(8.7, 29.6)

<0.001

 

16–24

29.9

0.4

73.7

(18.8, 289.4)

<0.001

 

25–44

3.5

0.1

26.6

(10.3, 68.5)

<0.001

 

45–64

4.7

0.2

21.8

(8.4, 56.9)

<0.001

B

All

1.9

1.1

1.6

(0.6, 4.3)

0.32

 

16–24

14.9

1.3

11.8

(1.7, 83.6)

0.002

 

25–44

0.9

0.2

3.7

(0.5, 26.1)

0.16

 

45–64

1.2

0.3

3.5

(0.5, 24.4)

0.19

C

All

1.4

0.05

27.1

(8.9, 82.4)

<0.001

 

16–24

-

0.1

-

-

-

 

25–44

1.8

0.05

35.1

(9.4, 131.4)

<0.001

 

45–64

1.2

0.03

32.0

(4.8, 212.8)

<0.001

Y

All

2.3

0.1

15.8

(6.7, 37.7)

<0.001

 

16–24

14.9

0.2

73.7

(10.7, 509.9)

<0.001

 

25–44

0.9

0.1

15.4

(2.3, 105.3)

<0.001

 

45–64

3.6

0.1

32.0

(10.7, 95.6)

<0.001

W

All

0.9

0.1

10.2

(2.6, 40.5)

<0.001

 

16–24

14.9

0.1

107.7

(15.8, 736.3)

<0.001

 

25–44

0.9

0.02

35.1

(5.4, 227.2)

<0.001

 

45–64

0.0

0.1

-

-

-