Multivariable odds ratio (95 % CI) | All data | Control arm patients only | Isoniazid arm patients only | Ethambutol arm patients only |
---|---|---|---|---|
Control | Reference | |||
Isoniazid | 1.81 (1.18, 2.78) | |||
Ethambutol | 2.88 (1.92, 4.33) | |||
p <0.001 | ||||
BMI per 1 kg/m2 | 0.92 (0.87, 0.98) | 0.93 (0.82, 1.05) | 0.95 (0.85, 1.05) | 0.90 (0.83, 0.99) |
p = 0.004 | p = 0.193 | p = 0.286 | p = 0.027 | |
History of smoking | 1.63 (1.15, 2.31) | 2.12 (0.99, 4.53) | 2.34 (1.23, 4.46) | 1.15 (0.69, 1.92) |
p = 0.005 | p = 0.046 | p = 0.007 | p = 0.592 | |
HIV positive | 2.93 (1.69, 5.08) | 2.64 (0.90, 7.78) | 1.95 (0.72, 5.28) | 4.46 (1.79, 11.09) |
p <0.001 | p = 0.100 | p = 0.210 | p = 0.002 | |
TTP on MGIT (per 0.1 log10(day)) | 0.97 (0.90, 1.05) | 1.17 (1.03, 1.32)a | 1.02 (0.89, 1.17) | 0.84 (0.74, 0.95) |
p = 0.439 | p = 0.024 | p = 0.789 | p = 0.003 | |
Male gender | 1.69 (1.13, 2.53) | 1.10 (0.48, 2.55) | 1.94 (0.94, 3.98) | 2.09 (1.13, 3.85) |
p = 0.009 | p = 0.817 | p = 0.060 | p = 0.014 | |
Cavities on X-ray | 1.93 (1.22, 3.05) | 1.62 (0.62, 4.19) | 2.82 (1.15, 6.94) | 1.75 (0.89, 3.41) |
p = 0.003 | p = 0.302 | p = 0.013 | p = 0.091 |