Table 1 Study participant demographic, socioeconomic, epidemiological and clinical characteristics
From: Rationing tests for drug-resistant tuberculosis – who are we prepared to miss?
All patients | Sputum culture negative for TB | Sputum culture positive for TB | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Drug-susceptible TBa | MDR-TB | Mono-resistant TBa | |||||||||||||||||
N | Unknown (n) | n | Unknown (n) | n | Unknown (n) | n | Unknown (n) | n | Unknown (n) | ||||||||||
Percentage of all subjects | Percentage of all patients | Percentage of all subjects | Percentage of all subjects | Percentage of all patients with drug sensitive TB | Percentage of all subjects | Percentage of patients with MDR-TB | Percentage of all subjects | Percentage of patients with mono-resistant TB | |||||||||||
Number of subjects | 1,545 | 100.0 | 1,398 | 90.5 | 0 | 115 | 7.4 | 100.0 | 0 | 20 | 1.3 | 100.0 | 0 | 12 | 0.8 | 100.0 | 0 | ||
Age (mean) | 36 | 0 | 37 | 0 | 32 | 0 | 32 | 0 | 32 | 0 | |||||||||
Male sex | 621 | 40.2 | 49.0 | 0 | 549 | 35.5 | 0 | 56 | 3.6 | 48.7 | 0 | 9 | 0.6 | 45.0 | 0 | 7 | 0.5 | 58.3 | 0 |
Smear positive | 82 | 5.3 | 50.3 | 0 | 8 | 0.5 | 0 | 60 | 3.9 | 52.2 | 0 | 11 | 0.7 | 55.0 | 0 | 3 | 0.2 | 25.0 | 0 |
Povertyb | 520 | 33.7 | 28.6 | 33 | 478 | 30.9 | 27 | 34 | 2.2 | 29.6 | 5 | 6 | 0.4 | 30.0 | 1 | 2 | 0.1 | 16.7 | 0 |
Overcrowdingc | 250 | 16.2 | 15.0 | 20 | 228 | 14.8 | 16 | 14 | 0.9 | 12.2 | 4 | 7 | 0.5 | 35.0 | 0 | 1 | 0.1 | 8.3 | 0 |
TB contact | 809 | 52.4 | 51.0 | 4 | 734 | 47.5 | 4 | 59 | 3.8 | 51.3 | 0 | 11 | 0.7 | 55.0 | 0 | 5 | 0.3 | 41.7 | 0 |
Smoker (current/ex) | 89 | 5.8 | 18.4 | 7 | 62 | 4.0 | 4 | 26 | 1.7 | 22.6 | 3 | 1 | 0.1 | 5.0 | 0 | 0 | 0.0 | 0.0 | 0 |
Drug user | 23 | 1.5 | 4.1 | 3 | 17 | 1.1 | 3 | 6 | 0.4 | 5.2 | 0 | 0 | 0.0 | 0.0 | 0 | 0 | 0.0 | 0.0 | 0 |
Excess alcohol | 185 | 12.0 | 19.7 | 3 | 156 | 10.1 | 3 | 25 | 1.6 | 21.7 | 0 | 3 | 0.2 | 15.0 | 0 | 1 | 0.1 | 8.3 | 0 |
Clinical information | |||||||||||||||||||
Prior BCG vaccine | 1,338 | 86.6 | 90.5 | 21 | 1,205 | 78.0 | 21 | 105 | 6.8 | 91.3 | 0 | 18 | 1.2 | 90.0 | 0 | 10 | 0.6 | 83.3 | 0 |
Cough | 1,290 | 83.5 | 87.1 | 1 | 1,162 | 75.2 | 1 | 101 | 6.5 | 87.8 | 0 | 17 | 1.1 | 85.0 | 0 | 10 | 0.6 | 83.3 | 0 |
Fever | 514 | 33.3 | 47.6 | 5 | 444 | 28.7 | 4 | 50 | 3.2 | 43.5 | 1 | 14 | 0.9 | 70.0 | 0 | 6 | 0.4 | 50.0 | 0 |
Haemoptysis | 238 | 15.4 | 31.3 | 5 | 192 | 12.4 | 5 | 41 | 2.7 | 35.7 | 0 | 3 | 0.2 | 15.0 | 0 | 2 | 0.1 | 16.7 | 0 |
Weight loss | 754 | 48.8 | 69.4 | 8 | 652 | 42.2 | 8 | 80 | 5.2 | 69.6 | 0 | 15 | 1.0 | 75.0 | 0 | 7 | 0.5 | 58.3 | 0 |
Night sweats | 567 | 36.7 | 49.0 | 8 | 495 | 32.0 | 7 | 54 | 3.5 | 47.0 | 1 | 12 | 0.8 | 60.0 | 0 | 6 | 0.4 | 50.0 | 0 |
Chest pain | 940 | 60.8 | 66.7 | 7 | 842 | 54.5 | 7 | 77 | 5.0 | 67.0 | 0 | 12 | 0.8 | 60.0 | 0 | 9 | 0.6 | 75.0 | 0 |
Breathlessness | 680 | 44.0 | 51.0 | 13 | 605 | 39.2 | 13 | 55 | 3.6 | 47.8 | 0 | 12 | 0.8 | 60.0 | 0 | 8 | 0.5 | 66.7 | 0 |