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Table 2 Study participant risk factors and microscopy and culture/drug-susceptible tuberculosis results

From: Rationing tests for drug-resistant tuberculosis – who are we prepared to miss?

 

All subjects

Sputum culture negative for TB

Sputum culture positive for TB

Drug-susceptible TB

MDR-TB

Mono-resistant TB

 

Unknown (n)

n

 

Unknown (n)

n

 

Unknown (n)

n

 

Unknown (n)

n

n

Percentage of all subjects

Percentage of all subjects

Percentage of all drug sensitive TB patients

Percentage of all subjects

Percentage of all MDR-TB patients

Percentage of all subjects

Percentage of all mono-resistant TB patients

All patients

1,545

1,398

90.5

0

115

7.4

100

0

20

1.3

100

0

12

0.8

100

0

≥1 MDR-TB-TB risk factora

553

506

32.8

0

32

2.1

27.8

0

11

0.7

55.0

0

4

0.3

33.3

0

≥1 MDR-TB risk factor or smear Positive sputumb

604

509

32.9

0

74

4.8

64.3

0

16

1.0

80.0

0

5

0.3

41.7

0

Previous TB

309

278

18.0

4

20

1.3

17.4

0

8

0.5

40.0

0

3

0.2

25.0

0

Known contact with MDR TB

161

153

9.9

8

3

0.2

2.6

0

3

0.2

15.0

0

2

0.1

16.7

0

Health worker

66

62

4.0

4

3

0.2

2.6

0

1

0.1

5.0

0

0

0.0

0.0

0

Current/ex prison worker or resident

38

32

2.1

4

5

0.3

4.3

0

1

0.1

5.0

0

0

0.0

0.0

0

HIV infection

18

18

1.2

4

0

0.0

0.0

1

0

0.0

0.0

0

0

0.0

0.0

0

  1. a MDR-TB risk factors as recommended by the WHO [10]; Previous TB treatment, Contact with known MDR-TBpatient), exposure to environments with high rates MDR TB (health care workers, prison workers & residents, previous hospitalisation), HIV infection
  2. bRepresents DST use as a follow on test after sputum microscopy
  3. TB, Tuberculosis; MDR-TB, Multidrug-resistant tuberculosis